The first domestically produced X-ray CT system with a photon counting detector is installed at the National Cancer Center Japan Exploratory Oncology Research & Clinical Trial Center

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TOKYO, November 7, 2022—Last year, Canon Inc. acquired Redlen Technologies Inc. (Redlen), one of the world’s leading companies in the creation of new technologies related to the development and manufacture of sensor modules at semiconductors1. Canon Medical Systems Corporation (Canon Medical), a Canon Inc. company, has developed the first2 Photon counting CT (PCCT)3 system incorporating advanced Redlen technologies. This system was installed at the National Cancer Center (NCC) Exploratory Oncology Research & Clinical Trial Center in Japan, where it is currently being used to conduct research exploring the clinical applications of PCCT.

An advanced modular photon counting detector based on the latest crystal production/processing technologies developed by Redlen Technologies Inc. is integrated into the PCCT system. The modular design of the photon counting detector allows for increased detector size while reducing manufacturing and maintenance costs. The modular detector supports a wide range of examinations and should meet the most demanding requirements of advanced clinical practice.

Researchers at CNC East Hospital

System operation

System operation

Based on a framework agreement4 signed in July 2020 and a collaborative basic research agreement signed in November 2020, NCC Exploratory Oncology Research & Clinical Trial Center, NCC Hospital East and Canon Medical have already started joint research5 promote the clinical application of PCCT. The results of this joint research aimed at improving the fundamental performance of PCCT were presented at the Annual Meeting of the Radiological Society of North America (RSNA 2021), the 2022 Annual Meeting of the Japanese Radiological Society, and the Annual Meeting of the European Society of Radiology (European Congress of Radiology, ECR 2022). Going forward, Canon will explore the new value offered by PCCT in a wide range of clinical areas, with the aim of promoting its rapid practical application.

Unlike conventional CT, in which X-rays are detected indirectly by a scintillator-type detector, PCCT detects X-rays directly using a photon-counting detector, which significantly improves baseline performance. The advantages of PCCT include reduced exposure dose compared to conventional CT, better detectability of lesions through higher resolution imaging, accurate discrimination and identification of various materials in the body, and tissue characterization and malignancy assessment based on quantitative image analysis. These advances are expected to improve diagnostic accuracy at all phases of clinical care, from prevention to diagnosis, through the assessment of treatment effects, as well as long-term prognosis.

Dr. Tatsushi Kobayashi (Head of Diagnostic Radiology at NCC Hospital East) says Canon’s CT systems have already achieved high resolution and include an advanced feature to differentiate and quantify materials in the body. This should improve tumor diagnosis by accurately identifying benign and malignant lesions and will also provide clearer images for evaluating treatment effects. Additionally, since cancer patients may need multiple follow-up exams, the dose reduction made possible by PCCT minimizes exposure to medical X-rays, allowing exams to be performed with greater peace of mind. of mind.

Mr. Toshio Takiguchi (Senior Executive of Canon Inc. and President and CEO of Canon Medical) asserts that Canon Medical is seeking to rapidly achieve the number one position in the global CT market by introducing next-generation PCCT systems incorporating the technologies of Redlen’s advanced manufacturing. as well as Canon Medical’s unique imaging technologies such as AI-based image reconstruction and analysis. In addition, by making Redlen’s photon-counting detectors available to other medical equipment manufacturers around the world, Canon Inc. will help promote the global development of diagnostic imaging technologies.

By strengthening its medical equipment business as one of the new businesses of the Canon Group, Canon Inc. aims to promote future growth and continue to contribute to healthcare worldwide.

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